After earning a degree in Film History from the University of Paris III, Pascal-Alex Vincent worked in the distribution of Japanese cinema in France.

Les Résultats du Bac, his first short film in 2001, marked the beginning of his collaboration with Local Films. His next short film, Far West (2002), was a success at festivals, followed in 2004 by Hollywood malgré lui, a comedy made as part of Canal+’s "Voilà comment tout a commencé" collection.

The Cannes Film Festival then selected Bébé Requin, a short film in competition for the Palme d’Or in 2005. Three years later, he completed post-production on his first feature film, Donne-moi la main, produced by Local Films.

In 2012, he began work on Miwa: A Japanease Icon, in Tokyo. The documentary focuses on Japanese actor and singer Akihiro Miwa. In October 2016, he published a dictionary of Japanese filmmakers (Carlotta Films Editions).